Skin eosinophilia from influenza viruses. An experimental histological study.
Identifieur interne : 003B03 ( Main/Exploration ); précédent : 003B02; suivant : 003B04Skin eosinophilia from influenza viruses. An experimental histological study.
Auteurs : L. Businco ; E. Bruzzese ; A. Scozzarro ; G. Servino ; S. Salsiccia ; A. Niro ; F. Ricciotti ; A. Altieri ; M. Corgiolu ; A. Di Nardo ; A. Leoni ; L. Mancini ; C. Oddo ; A. Pelle ; A. Pitzalis ; F. Pitzalis ; C. Bancheri ; V. Ragno ; G. Mesiano ; L. VitaliSource :
- Allergologia et immunopathologia [ 0301-0546 ]
Descripteurs français
- KwdFr :
- Animaux, Asthme (étiologie), Cochons d'Inde, Infections à Orthomyxoviridae (), Lapins, Maladies de la peau (anatomopathologie), Maladies de la peau (microbiologie), Maladies de la peau (étiologie), Modèles animaux de maladie humaine, Orthomyxoviridae, Éosinophilie (anatomopathologie), Éosinophilie (étiologie).
- MESH :
- anatomopathologie : Maladies de la peau, Éosinophilie.
- microbiologie : Maladies de la peau.
- étiologie : Asthme, Maladies de la peau, Éosinophilie.
- Animaux, Cochons d'Inde, Infections à Orthomyxoviridae, Lapins, Modèles animaux de maladie humaine, Orthomyxoviridae.
English descriptors
- KwdEn :
- MESH :
- complications : Orthomyxoviridae Infections.
- etiology : Asthma, Eosinophilia, Skin Diseases.
- microbiology : Skin Diseases.
- pathology : Eosinophilia, Skin Diseases.
- Animals, Disease Models, Animal, Guinea Pigs, Orthomyxoviridae, Rabbits.
Abstract
The authors would first like to stress the increasing frequency of bronchial asthma during or after influenza. To find an explanation for this occurrence they observed tissue reactions following an injection of viral material. In their experiments, they injected into the skin of guinea pigs, strains of the Hong Kong, Texas and USSR influenza viruses using current vaccines, sacrificing groups of animals 2, 6, 24, 48 hours and 7 days after the injection. The histological study revealed the following picture of reaction to influenza viruses. Two hours after the injection: marked and diffuse infiltration of eosinophils in the connective tissue of the skin. After 6 hours: the infiltration shows a predominance of neutrophils. After 24 hours: the neutrophil infiltration is predominant and diffuse. There is evidence of considerable degranulation of eosinophils. The cutaneous histiocytes undergo fibrocytic and marcophagic proliferation. After 28 hours, the same picture. After 7 days there is sever degeneration with a peripheral fibroblastic reaction. The most important finding of this experiment is the early marked infiltration of eosinophils which follows the injection of the influenza viruses. The eosinophil infiltration appears to be related to the release of histamine caused by influenza viruses. The histological examination did not reveal the presence of immune allergic-type cells at any time. Therefore, the onset of asthmatic attacks would appear to be more related to the histamine-releasing action of the influenza viruses rather than to their sensitizing activity. Naturally, the latter may occur in human pathologies.
PubMed: 7468394
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000B23
- to stream PubMed, to step Curation: 000B20
- to stream PubMed, to step Checkpoint: 000B39
- to stream Ncbi, to step Merge: 001141
- to stream Ncbi, to step Curation: 001141
- to stream Ncbi, to step Checkpoint: 001141
- to stream Main, to step Merge: 003B22
- to stream Main, to step Curation: 003B03
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Skin eosinophilia from influenza viruses. An experimental histological study.</title><author><name sortKey="Businco, L" sort="Businco, L" uniqKey="Businco L" first="L" last="Businco">L. Businco</name></author><author><name sortKey="Bruzzese, E" sort="Bruzzese, E" uniqKey="Bruzzese E" first="E" last="Bruzzese">E. Bruzzese</name></author><author><name sortKey="Scozzarro, A" sort="Scozzarro, A" uniqKey="Scozzarro A" first="A" last="Scozzarro">A. Scozzarro</name></author><author><name sortKey="Servino, G" sort="Servino, G" uniqKey="Servino G" first="G" last="Servino">G. Servino</name></author><author><name sortKey="Salsiccia, S" sort="Salsiccia, S" uniqKey="Salsiccia S" first="S" last="Salsiccia">S. Salsiccia</name></author><author><name sortKey="Niro, A" sort="Niro, A" uniqKey="Niro A" first="A" last="Niro">A. Niro</name></author><author><name sortKey="Ricciotti, F" sort="Ricciotti, F" uniqKey="Ricciotti F" first="F" last="Ricciotti">F. Ricciotti</name></author><author><name sortKey="Altieri, A" sort="Altieri, A" uniqKey="Altieri A" first="A" last="Altieri">A. Altieri</name></author><author><name sortKey="Corgiolu, M" sort="Corgiolu, M" uniqKey="Corgiolu M" first="M" last="Corgiolu">M. Corgiolu</name></author><author><name sortKey="Di Nardo, A" sort="Di Nardo, A" uniqKey="Di Nardo A" first="A" last="Di Nardo">A. Di Nardo</name></author><author><name sortKey="Leoni, A" sort="Leoni, A" uniqKey="Leoni A" first="A" last="Leoni">A. Leoni</name></author><author><name sortKey="Mancini, L" sort="Mancini, L" uniqKey="Mancini L" first="L" last="Mancini">L. Mancini</name></author><author><name sortKey="Oddo, C" sort="Oddo, C" uniqKey="Oddo C" first="C" last="Oddo">C. Oddo</name></author><author><name sortKey="Pelle, A" sort="Pelle, A" uniqKey="Pelle A" first="A" last="Pelle">A. Pelle</name></author><author><name sortKey="Pitzalis, A" sort="Pitzalis, A" uniqKey="Pitzalis A" first="A" last="Pitzalis">A. Pitzalis</name></author><author><name sortKey="Pitzalis, F" sort="Pitzalis, F" uniqKey="Pitzalis F" first="F" last="Pitzalis">F. Pitzalis</name></author><author><name sortKey="Bancheri, C" sort="Bancheri, C" uniqKey="Bancheri C" first="C" last="Bancheri">C. Bancheri</name></author><author><name sortKey="Ragno, V" sort="Ragno, V" uniqKey="Ragno V" first="V" last="Ragno">V. Ragno</name></author><author><name sortKey="Mesiano, G" sort="Mesiano, G" uniqKey="Mesiano G" first="G" last="Mesiano">G. Mesiano</name></author><author><name sortKey="Vitali, L" sort="Vitali, L" uniqKey="Vitali L" first="L" last="Vitali">L. Vitali</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>1980 Sep-Oct</MedlineDate></PubDate></date><idno type="RBID">pubmed:7468394</idno><idno type="pmid">7468394</idno><idno type="wicri:Area/PubMed/Corpus">000B23</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B23</idno><idno type="wicri:Area/PubMed/Curation">000B20</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B20</idno><idno type="wicri:Area/PubMed/Checkpoint">000B39</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000B39</idno><idno type="wicri:Area/Ncbi/Merge">001141</idno><idno type="wicri:Area/Ncbi/Curation">001141</idno><idno type="wicri:Area/Ncbi/Checkpoint">001141</idno><idno type="wicri:doubleKey">0301-0546::Businco L:skin:eosinophilia:from</idno><idno type="wicri:Area/Main/Merge">003B22</idno><idno type="wicri:Area/Main/Curation">003B03</idno><idno type="wicri:Area/Main/Exploration">003B03</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Skin eosinophilia from influenza viruses. An experimental histological study.</title><author><name sortKey="Businco, L" sort="Businco, L" uniqKey="Businco L" first="L" last="Businco">L. Businco</name></author><author><name sortKey="Bruzzese, E" sort="Bruzzese, E" uniqKey="Bruzzese E" first="E" last="Bruzzese">E. Bruzzese</name></author><author><name sortKey="Scozzarro, A" sort="Scozzarro, A" uniqKey="Scozzarro A" first="A" last="Scozzarro">A. Scozzarro</name></author><author><name sortKey="Servino, G" sort="Servino, G" uniqKey="Servino G" first="G" last="Servino">G. Servino</name></author><author><name sortKey="Salsiccia, S" sort="Salsiccia, S" uniqKey="Salsiccia S" first="S" last="Salsiccia">S. Salsiccia</name></author><author><name sortKey="Niro, A" sort="Niro, A" uniqKey="Niro A" first="A" last="Niro">A. Niro</name></author><author><name sortKey="Ricciotti, F" sort="Ricciotti, F" uniqKey="Ricciotti F" first="F" last="Ricciotti">F. Ricciotti</name></author><author><name sortKey="Altieri, A" sort="Altieri, A" uniqKey="Altieri A" first="A" last="Altieri">A. Altieri</name></author><author><name sortKey="Corgiolu, M" sort="Corgiolu, M" uniqKey="Corgiolu M" first="M" last="Corgiolu">M. Corgiolu</name></author><author><name sortKey="Di Nardo, A" sort="Di Nardo, A" uniqKey="Di Nardo A" first="A" last="Di Nardo">A. Di Nardo</name></author><author><name sortKey="Leoni, A" sort="Leoni, A" uniqKey="Leoni A" first="A" last="Leoni">A. Leoni</name></author><author><name sortKey="Mancini, L" sort="Mancini, L" uniqKey="Mancini L" first="L" last="Mancini">L. Mancini</name></author><author><name sortKey="Oddo, C" sort="Oddo, C" uniqKey="Oddo C" first="C" last="Oddo">C. Oddo</name></author><author><name sortKey="Pelle, A" sort="Pelle, A" uniqKey="Pelle A" first="A" last="Pelle">A. Pelle</name></author><author><name sortKey="Pitzalis, A" sort="Pitzalis, A" uniqKey="Pitzalis A" first="A" last="Pitzalis">A. Pitzalis</name></author><author><name sortKey="Pitzalis, F" sort="Pitzalis, F" uniqKey="Pitzalis F" first="F" last="Pitzalis">F. Pitzalis</name></author><author><name sortKey="Bancheri, C" sort="Bancheri, C" uniqKey="Bancheri C" first="C" last="Bancheri">C. Bancheri</name></author><author><name sortKey="Ragno, V" sort="Ragno, V" uniqKey="Ragno V" first="V" last="Ragno">V. Ragno</name></author><author><name sortKey="Mesiano, G" sort="Mesiano, G" uniqKey="Mesiano G" first="G" last="Mesiano">G. Mesiano</name></author><author><name sortKey="Vitali, L" sort="Vitali, L" uniqKey="Vitali L" first="L" last="Vitali">L. Vitali</name></author></analytic><series><title level="j">Allergologia et immunopathologia</title><idno type="ISSN">0301-0546</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Asthma (etiology)</term><term>Disease Models, Animal</term><term>Eosinophilia (etiology)</term><term>Eosinophilia (pathology)</term><term>Guinea Pigs</term><term>Orthomyxoviridae</term><term>Orthomyxoviridae Infections (complications)</term><term>Rabbits</term><term>Skin Diseases (etiology)</term><term>Skin Diseases (microbiology)</term><term>Skin Diseases (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Asthme (étiologie)</term><term>Cochons d'Inde</term><term>Infections à Orthomyxoviridae ()</term><term>Lapins</term><term>Maladies de la peau (anatomopathologie)</term><term>Maladies de la peau (microbiologie)</term><term>Maladies de la peau (étiologie)</term><term>Modèles animaux de maladie humaine</term><term>Orthomyxoviridae</term><term>Éosinophilie (anatomopathologie)</term><term>Éosinophilie (étiologie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Maladies de la peau</term><term>Éosinophilie</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Asthma</term><term>Eosinophilia</term><term>Skin Diseases</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Maladies de la peau</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Skin Diseases</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Eosinophilia</term><term>Skin Diseases</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Asthme</term><term>Maladies de la peau</term><term>Éosinophilie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Guinea Pigs</term><term>Orthomyxoviridae</term><term>Rabbits</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Cochons d'Inde</term><term>Infections à Orthomyxoviridae</term><term>Lapins</term><term>Modèles animaux de maladie humaine</term><term>Orthomyxoviridae</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The authors would first like to stress the increasing frequency of bronchial asthma during or after influenza. To find an explanation for this occurrence they observed tissue reactions following an injection of viral material. In their experiments, they injected into the skin of guinea pigs, strains of the Hong Kong, Texas and USSR influenza viruses using current vaccines, sacrificing groups of animals 2, 6, 24, 48 hours and 7 days after the injection. The histological study revealed the following picture of reaction to influenza viruses. Two hours after the injection: marked and diffuse infiltration of eosinophils in the connective tissue of the skin. After 6 hours: the infiltration shows a predominance of neutrophils. After 24 hours: the neutrophil infiltration is predominant and diffuse. There is evidence of considerable degranulation of eosinophils. The cutaneous histiocytes undergo fibrocytic and marcophagic proliferation. After 28 hours, the same picture. After 7 days there is sever degeneration with a peripheral fibroblastic reaction. The most important finding of this experiment is the early marked infiltration of eosinophils which follows the injection of the influenza viruses. The eosinophil infiltration appears to be related to the release of histamine caused by influenza viruses. The histological examination did not reveal the presence of immune allergic-type cells at any time. Therefore, the onset of asthmatic attacks would appear to be more related to the histamine-releasing action of the influenza viruses rather than to their sensitizing activity. Naturally, the latter may occur in human pathologies.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Altieri, A" sort="Altieri, A" uniqKey="Altieri A" first="A" last="Altieri">A. Altieri</name><name sortKey="Bancheri, C" sort="Bancheri, C" uniqKey="Bancheri C" first="C" last="Bancheri">C. Bancheri</name><name sortKey="Bruzzese, E" sort="Bruzzese, E" uniqKey="Bruzzese E" first="E" last="Bruzzese">E. Bruzzese</name><name sortKey="Businco, L" sort="Businco, L" uniqKey="Businco L" first="L" last="Businco">L. Businco</name><name sortKey="Corgiolu, M" sort="Corgiolu, M" uniqKey="Corgiolu M" first="M" last="Corgiolu">M. Corgiolu</name><name sortKey="Di Nardo, A" sort="Di Nardo, A" uniqKey="Di Nardo A" first="A" last="Di Nardo">A. Di Nardo</name><name sortKey="Leoni, A" sort="Leoni, A" uniqKey="Leoni A" first="A" last="Leoni">A. Leoni</name><name sortKey="Mancini, L" sort="Mancini, L" uniqKey="Mancini L" first="L" last="Mancini">L. Mancini</name><name sortKey="Mesiano, G" sort="Mesiano, G" uniqKey="Mesiano G" first="G" last="Mesiano">G. Mesiano</name><name sortKey="Niro, A" sort="Niro, A" uniqKey="Niro A" first="A" last="Niro">A. Niro</name><name sortKey="Oddo, C" sort="Oddo, C" uniqKey="Oddo C" first="C" last="Oddo">C. Oddo</name><name sortKey="Pelle, A" sort="Pelle, A" uniqKey="Pelle A" first="A" last="Pelle">A. Pelle</name><name sortKey="Pitzalis, A" sort="Pitzalis, A" uniqKey="Pitzalis A" first="A" last="Pitzalis">A. Pitzalis</name><name sortKey="Pitzalis, F" sort="Pitzalis, F" uniqKey="Pitzalis F" first="F" last="Pitzalis">F. Pitzalis</name><name sortKey="Ragno, V" sort="Ragno, V" uniqKey="Ragno V" first="V" last="Ragno">V. Ragno</name><name sortKey="Ricciotti, F" sort="Ricciotti, F" uniqKey="Ricciotti F" first="F" last="Ricciotti">F. Ricciotti</name><name sortKey="Salsiccia, S" sort="Salsiccia, S" uniqKey="Salsiccia S" first="S" last="Salsiccia">S. Salsiccia</name><name sortKey="Scozzarro, A" sort="Scozzarro, A" uniqKey="Scozzarro A" first="A" last="Scozzarro">A. Scozzarro</name><name sortKey="Servino, G" sort="Servino, G" uniqKey="Servino G" first="G" last="Servino">G. Servino</name><name sortKey="Vitali, L" sort="Vitali, L" uniqKey="Vitali L" first="L" last="Vitali">L. Vitali</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003B03 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003B03 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= StressCovidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:7468394
|texte= Skin eosinophilia from influenza viruses. An experimental histological study.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:7468394" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a StressCovidV1
| This area was generated with Dilib version V0.6.33. |  |